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wwPDB: Worldwide Protein Data Bank

发布时间:2026-09-21 | 浏览:2
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Since 1971, the Protein Data Bank archive (PDB) has served as the single repository of information about the 3D structures of proteins, nucleic acids, and complex assemblies. Celebrating 50 Years of the PDB The Worldwide PDB (wwPDB) organization manages the PDB archive and ensures that the PDB is freely and publicly available to the global community. Celebrating 20 Years of the wwPDB Partnership Validate Structure or View validation reports Deposit Structure All Deposition Resources Download Archive Sustain freely accessible, interoperating Core Archives of structure data and metadata for biological macromolecules as an enduring public good to promote basic and applied research and education across the sciences. Manage the wwPDB Core Archives as a public good according to the FAIR Principles. Provide expert deposition, validation, biocuration, and remediation services at no charge to Data Depositors worldwide. Ensure universal open access to public domain structural biology data with no limitations on usage. Develop and promote community-endorsed data standards for archiving and exchange of global structural biology data. Rich information about all PDB entries, multiple search and browse facilities, advanced services including PDBePISA, PDBeFold and PDBeMotif, advanced visualisation and validation of NMR and EM structures, tools for bioinformaticians. Collects 3D volumes & associated information of macromolecular complexes & subcellular structures from electron cryo microscopy & electron cryo tomography; develops resources for searching, data mining, analyzing, validating & visualizing data. Simple and advanced searching for macromolecules and ligands, flexible APIs for programmatic users, specialized 1D-3D visualization tools, Molecule of the Month and other training resources at PDB-101, and more. Collects NMR data from any experiment and captures assigned chemical shifts, coupling constants, and peak lists for a variety of macromolecules; contains derived annotations such as hydrogen exchange rates, pKa values, and relaxation parameters. Protein Data Bank China (PDBc) has joined Worldwide Protein Data Bank (wwPDB) as an Associate Member in 2022. PDBc is based in the National Facility for Protein Science in Shanghai which is associated with the Shanghai Advanced Research Institute of Chinese Academy of Sciences, the Shanghai Institute for Advanced Immunochemical Studies and the iHuman Institute of ShanghaiTech University. Multilingual access (English, Japanese, Chinese, and Korean) and comprehensive structural tools, including advanced querying (PDBj Mine), shape similarity search (Omokage), and visualization (Molmil). Maintains unique archives for computational models (BSM-Arc) and raw diffraction data (XRDa). Data Dictionaries Macromolecular Dictionary (PDBx/mmCIF) Small Molecule Dictionary (CCD) Peptide-like antibiotic and inhibitor molecules (BIRD)
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Procedures and policies Improvements for consistency and accuracy Community Input: Task Forces and Working Groups Validation Task Forces (X-ray, NMR, 3DEM) Small Angle Scattering Task Force PDBx/mmCIF Working Group Hybrid/Integrative Methods Task Force Ligand Validation Workshop ModelCIF Working Group PDB Data Growth & Usage Statistics Depositions: by data center, by year, and by depositor location Downloads: by year for all entries Workshops & Symposia 2021: Celebrating 50 Years of the PDB Summaries and presentations from past meetings and events Information for Journals Policies, procedures, coordination with publishers, and preferred Instructions to Authors Cite the PDB archive: Poster Prizes Awarded at IUCr Congratulations to Philip Rushton (Purdue University) and Ryu Williston (McGill University) Remediation of Metal-containing PDB Entries and CCDs Improved accuracy and annotation metal-containing PDB Entries and CCDs are now available in remediated PDB data. Paper Published about the PDB Beta Archive Read about changes that will become the default on July 21, 2027. Transition to this new architecture today.
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