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RCSB Protein Data Bank (RCSB PDB) enables breakthroughs in science and education by providing access and tools for exploration, visualization, and analysis of:
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Computed Structure Models (CSM) from AlphaFold DB and ModelArchive
September Molecule of the Month
Deposit via OneDep Deposition and annotation systems unified across all wwPDB deposition centers
Deposit via OneDep
Deposition and annotation systems unified across all wwPDB deposition centers
Prepare Files via pdb_extract Convert PDB file to mmCIF format and extract meta data and statistical information
Prepare Files via pdb_extract
Convert PDB file to mmCIF format and extract meta data and statistical information
Validate Structures Search protein structures by global shape similarity
Validate Structures
Search protein structures by global shape similarity
PDBx/mmCIF Dictionary Resources Information about the format, dictionaries, and related software tools used by the wwPDB
PDBx/mmCIF Dictionary Resources
Information about the format, dictionaries, and related software tools used by the wwPDB
Other Deposition Resources Help page summarizing tools available for deposition and validation
Other Deposition Resources
Help page summarizing tools available for deposition and validation
Advanced Search Complex boolean queries with values for a wide range of structure attributes
Advanced Search
Complex boolean queries with values for a wide range of structure attributes
Sequence Similarity Search Find similar protein and nucleic acid sequences using the mmseqs2 method
Sequence Similarity Search
Find similar protein and nucleic acid sequences using the mmseqs2 method
3D Similarity Search Search protein structures by global shape similarity
3D Similarity Search
Search protein structures by global shape similarity
Chemical Similarity Search Search for small molecules using SMILES, InChI, or Chemical Formula
Chemical Similarity Search
Search for small molecules using SMILES, InChI, or Chemical Formula
Browse by Annotations PDB entries in context of annotations by various ontologies and hierarchical classification schemes
Browse by Annotations
PDB entries in context of annotations by various ontologies and hierarchical classification schemes
New Entries Search entries released since last Tuesday
Search entries released since last Tuesday
Unreleased Entries Search entries that are being processed, on hold waiting for release, or have been withdrawn
Unreleased Entries
Search entries that are being processed, on hold waiting for release, or have been withdrawn
PDB Statistics PDB data distribution, archive growth, and more
PDB data distribution, archive growth, and more
Mol* (MolStar) 3D visualization for PDB structures and ligand binding sites. Access from each structure summary page.
3D visualization for PDB structures and ligand binding sites. Access from each structure summary page.
Sequence Annotations Viewer Graphical summaries of protein features and their relationships with UniProtKB entries. Access from each structure summary page.
Sequence Annotations Viewer
Graphical summaries of protein features and their relationships with UniProtKB entries. Access from each structure summary page.
Genome View Graphical summaries of the correspondences between PDB entity sequences and genomes. Access from each structure summary page.
Graphical summaries of the correspondences between PDB entity sequences and genomes. Access from each structure summary page.
Pairwise Structure Alignment Calculate pairwise structure alignments using various methods
Pairwise Structure Alignment
Calculate pairwise structure alignments using various methods
Symmetry Resources in the PDB Explore tools that display global, local, and helical symmetry among subunits
Symmetry Resources in the PDB
Explore tools that display global, local, and helical symmetry among subunits
Structure Quality The slider graphic compares important global quality indicators for a given structure with the PDB archive
Structure Quality
The slider graphic compares important global quality indicators for a given structure with the PDB archive
Grouping Structures Explore conservation and trends in the structure properties, features, and functions
Grouping Structures
Explore conservation and trends in the structure properties, features, and functions
PDB Citation MeSH Network Explorer Find connections between articles describing PDB structures using MeSH terms
PDB Citation MeSH Network Explorer
Find connections between articles describing PDB structures using MeSH terms
PDB Statistics PDB data distribution, archive growth, and more
PDB data distribution, archive growth, and more
EPPIC Biological Assemblies EPPIC (Evolutionary Protein-Protein Interface Classifier) finds biological interfaces from crystal contacts
EPPIC Biological Assemblies
EPPIC (Evolutionary Protein-Protein Interface Classifier) finds biological interfaces from crystal contacts
External Data and Resources • Integrated Resources • Additional Resources
External Data and Resources
• Integrated Resources
• Additional Resources
Coordinates and Experimental Data Enter PDB IDs to download multiple files in batches containing one or more file formats
Coordinates and Experimental Data
Enter PDB IDs to download multiple files in batches containing one or more file formats
Sequences Enter PDB IDs to download sequences in FASTA format
Enter PDB IDs to download sequences in FASTA format
Ligands Enter the chemical component IDs to download SDF files with ligand coordinates
Enter the chemical component IDs to download SDF files with ligand coordinates
File Download Services Download PDB archive or other related data files
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Web APIs The Data API and Search API are the two main APIs that power rcsb.org
The Data API and Search API are the two main APIs that power rcsb.org
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Training Courses Learn to effectively use tools for deposition, searching, analysis, and visualization of PDB data
Training Courses
Learn to effectively use tools for deposition, searching, analysis, and visualization of PDB data
Guide to PDB Data Guided reference for exploration and interpretation of PDB entries
Guide to PDB Data
Guided reference for exploration and interpretation of PDB entries
Molecule of the Month Accounts of selected molecules from the PDB
Molecule of the Month
Accounts of selected molecules from the PDB
Educational Resources Resources promoting exploration in the world of proteins and nucleic acids
Educational Resources
Resources promoting exploration in the world of proteins and nucleic acids
Curricula Authentic, hands-on teaching materials, individual and group activities
Authentic, hands-on teaching materials, individual and group activities
Browse Browse all PDB-101 resources by biological theme
Browse all PDB-101 resources by biological theme
News Learn about educational offerings and outreach events
Learn about educational offerings and outreach events
SciArt Galleries Molecular art for downloading and printing by • Irving Geis • David Goodsell
SciArt Galleries
Molecular art for downloading and printing by
• David Goodsell
KRAS-specific 24-246 TCR in complex with HLA-C*01:02 presenting KRAS G12V 9mer peptide (11-AVGVGKSAL-19)
Structure of RY12 domain of rabbit RyR1 complexed with dantrolene and ADP
Human CCT in Closed Conformation
Full-length structure of catalytically inactivated LysC from Pseudomonas aeruginosa
Crystal structure of the human galectin-3 carbohydrate-recognition domain in the apo form
CryoEM Structure of human MDA5 disease-linked mutant T331I with dsRNA (one protein subunit on dsRNA)
Crystal structure of xanthine/guanine RNA aptamer (P1-12bp) with hypoxanthine
VIPR Ternary Complex with a duplex dsDNA substrate, 10 subunits
VIPR Ternary Complex with a duplex dsDNA substrate, 5 subunits
Zuzalysin active bi-pentamer
Register for the Oct 22 Virtual Office Hour on Transitioning to the New PDB Beta Archive, Extended PDB IDs, and PDBx/mmCIF
Learn how to prepare for the July 21, 2027 transition, including using shortlinks in your code. This Office Hour is for all users, but particularly for software developers and journal editors.
Poster Prizes Awarded at IUCr
Congratulations to Philip Rushton (Purdue University) and Ryu Williston (McGill University)
Guide to Understanding PDB Data: Metalloproteins
Visit PDB-101 for an Introduction to Metalloproteins in the PDB
Register for the Sept 17 Webinar on Remediated Metalloprotein Data in the PDB
Learn how metalloprotein data have been enhanced to support the Findability, Accessibility, Interoperability, and Reusability of PDB data
Remediation of Metal-containing PDB Entries and CCDs
Improved accuracy and annotation metal-containing PDB Entries and CCDs are now available in remediated PDB data.
Paper Published about the PDB Beta Archive
Read about changes that will become the default on July 21, 2027. Transition to this new architecture today.
Use Shortlinks to Transition to the PDB Beta Archive
The PDB Beta Archive will replace the current archive July 21, 2027. Shortlinks are available now to help programmatic users with this transition.
New tools support deposition of structures to the wwPDB PDB and 3DEM Core Archives directly from structure determination software packages
Upload structures to the wwPDB OneDep system directly from refinement software packages
Reuse Metadata from Previous PDB Depositions
The refactored “Based on previous” workflow allows depositors to selectively import and reuse mmCIF metadata from a previously deposited PDB entry with method-aware safeguards, macromolecule checks, ORCID search, and transparent import logging.
Big PDB Changes Are One Year Away: Extended PDB IDs, the PDB Beta Archive, and PDBx/mmCIF
On July 21, 2027, the wwPDB will fully transition to extended PDB IDs for new depositions and the PDB archive will use a new directory structure based on 12-character extended PDB IDs. Users should adopt these upcoming changes today.
Publications Published in Journals & Books Molecule of the Month Quarterly Newsletter Annual Report
Published in Journals & Books
Molecule of the Month
Quarterly Newsletter
Poster Prize Awarded at ISMB
Congratulations to Gabriel J. Olguín-Orellana (University of Concepción) for PIP 2 Binding at the TMIE-TMC1 Interface Reveals a Putative Lipid Regulatory Site in the Hair-Cell MET Channel .
PDB-101 Focus: Biotechnology
PDB-101 materials explore how researchers are using biology in industry, such as CRISPR
Education Corner: Solving Structures, Enabling Discovery
Learn about The Impact of the CRSTAL-ID Centers in the latest newsletter
Software Developers: Join our Team at Rutgers
RCSB PDB is looking for a software database administrator/database specialist and an IT Infrastructure Lead to support the ongoing operations and growth of our IT infrastructure.
Impact of PDB Structures on Anti-Cancer Drug Approvals
Open access to PDB data facilitates discovery and development of life saving drugs.
Watch the Webinar: Advanced Search
Learn what is new in the redesigned Advanced Search feature and how to use it
PDB-101 Focus: Biotechnology
PDB-101 materials explore how researchers are using biology in industry. Phytase is used to mobilize indigestible phosphate compounds in livestock feed
White Paper on Fragment Screening Workshop Available
Read community recommendations for deposition and reuse of high-throughput structural biology data from fragment screening, hit-to-lead studies, and lead-optimization campaigns ( PDF )
Guide to Understanding PDB Data: 3D ED/MicroED
Visit PDB-101 for an Introduction to Microcrystal Electron Diffraction
wwPDB Events at IUCr
Meet team members from around the globe at the International Union of Crystallography meeting in Calgary
Molecule of the Month
Bacterial communities glued together and protected by biological polymers
Quarterly News (see archive )
Issue 110 - July 2026
This issue highlights Extended PDB IDs; updates to predicted Computer Structure Models at RCSB.org, and PDB-101 resources for exploring protein domains.
Spring 2026 Issue
Winter 2026 Issue
Fall 2025 Issue
2025 Annual Report
Download the 2025 Annual Report ( PDF ) for an overview of recent activities and the global impact of PDB data and RCSB PDB services.
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